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Image Search Results
Journal: Nutrients
Article Title: Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice
doi: 10.3390/nu11102354
Figure Lengend Snippet: Effects of oral administration of hydrangenol on STAT1, AP-1, and the mitogen-activated protein kinase (MAPK) signaling pathway in UVB-irradiated hairless mice. HR-1 hairless mice were administered hydrangenol (5, 10, 20, or 40 mg/kg) daily for 7 weeks of exposure to UVB. Total proteins were extracted from dorsal skin tissues. The phosphorylation and expression of target proteins were estimated using Western blotting using specific p-STAT1 (S727), p-c-Fos, p-c-Jun, p-p38, phospho-extracellular signal-regulated kinase (p-ERK), and phospho-c-Jun N-terminal kinase (p-JNK) antibodies. The internal control was a β-actin protein. Representative blots of ( A ) STAT1, AP-1, and ( B ) MAPK signaling proteins. Each band is representative of three experiments.
Article Snippet: The phospho-c-Fos (#5348),
Techniques: Irradiation, Phospho-proteomics, Expressing, Western Blot, Control